Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist originally developed for type 2 diabetes management. It has demonstrated significant efficacy for weight management by reducing appetite, slowing gastric emptying, and improving glycemic control.

Semaglutide mimics endogenous GLP-1, binding to GLP-1 receptors in the pancreas, gut, and brain. It stimulates insulin secretion, suppresses glucagon release, slows gastric emptying, and acts on hypothalamic appetite centers to reduce hunger and promote satiety.
Common side effects include nausea, vomiting, and diarrhea, which typically improve as the body adjusts during dose titration. Semaglutide should not be used in patients with a personal or family history of medullary thyroid carcinoma or MEN 2 syndrome.
Speak with a licensed clinician to find out if Semaglutide is right for your protocol.
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