Hormone Therapy — BHRT

Pregnenolone

Pregnenolone is often called the 'mother hormone' because it sits at the top of the steroid hormone synthesis cascade. Derived from cholesterol, it is the precursor to DHEA, progesterone, cortisol, estrogen, and testosterone. Supplementation supports cognitive function, mood, and hormonal harmony.

Available Delivery Methods

Oral CapsuleTopical Cream

Why Pregnenolone

Key Benefits

Master precursor to all steroid hormones
Supports cognitive function and memory
May improve mood and reduce stress
Supports overall hormonal balance and resilience
Well tolerated at therapeutic doses

The Science

How It Works

Pregnenolone is synthesized from cholesterol in the mitochondria and serves as the obligate precursor for all steroid hormones. It is also a neurosteroid that modulates GABA-A and NMDA receptors, influencing cognitive function, memory consolidation, and neuroprotection.

Safety & Side Effects

Pregnenolone is generally well tolerated. Because it feeds into multiple hormonal pathways, hormone levels should be monitored during therapy. Potential side effects include mild headache, irritability, or insomnia at higher doses.

Hormone Therapy — BHRT