Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor widely prescribed for erectile dysfunction. Distinguished by its long duration of action (up to 36 hours), it allows for greater spontaneity and is also used at lower daily doses for benign prostatic hyperplasia symptoms.


Tadalafil selectively inhibits phosphodiesterase type 5 (PDE5), preventing the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels promote smooth muscle relaxation and increased blood flow in the corpus cavernosum, facilitating erectile response to sexual stimulation.
Common side effects include headache, indigestion, back pain, and nasal congestion. Tadalafil must not be used with nitrate medications due to the risk of severe hypotension. Patients with cardiovascular conditions should discuss risks with their clinician.
Speak with a licensed clinician to find out if Tadalafil is right for your protocol.
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